The roles of organic degradation products andselenium in the pathogenesis ofKaschin-Beck disease |
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Authors: | Wang Weizhe Feng Lanfei Ren Hongwei Wang Xiaoying |
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Affiliation: | Wang Weizhe,Feng Lanfei,Ren Hongwei and Wang XiaoyingDepartment of Pathophysiology,Liaoning Instiule of Basic Medicine,shenyang 11005,China |
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Abstract: | An investigation on the organic degradation products and selenium in the pathogenesis of Kaschin-Beck disease was carried out. The results demonstrated that the organic degradation products existed in food and drinking water were the pathogens of the KBD; their leading pathological process of cells would be "membrane injury" due to peroxide. As GSH-Px is a selenium contained enzyme, therefore insufficient selenium would be one of the most important conditions to cause KBD. |
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Keywords: | Kaschin-Beck disease humic adds sdenium antioxidase lipid peroxide. |
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