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Selective accumulation of chlorinated paraffins (C12 and C16) in the olfactory organ of rainbow trout |
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| Authors: | PO Darnerud Bergman BO Lund and I Brandt |
| Institution: | 1Environmental Chemistry, Wallenberg Laboratory, Stockholm University, S-106 91 Stockholm, Sweden 2Department of Pharmacology and Toxicology, Swedish University of Agricultural Sciences, BMC, Box 573, S-751 23 Uppsala, Sweden 3Department of Toxicology, Uppsala University, BMC, Box 594, S-751 24 Uppsala, Sweden |
| Abstract: | Three 14C-labelled polychloroalkanes (C12 and C16), representing low (23% Cl by weight), medium (51%), and highly (68%) chlorinated paraffin (CP) mixtures, were presented to rainbow trout via the water. The uptake in fat-rich tissues was positively correlated to the degree of chlorination of the preparations. Notably, all preparations gave rise to a high and selective uptake of radioactivity in the olfactory organ and gills. This selective radiolabelling may reflect a general ability of these organs to enrich xenobiotics from the surrounding water. The olfactory organ may be a hitherto unforseen target for toxic environmental pollutants in fish. |
| Keywords: | Chlorinated paraffins 14C-labelled polychloroalkanes olfactory organ gills rainbow trout |
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