Some effect of CuSO4 on carp |
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| Authors: | L Tóth M Juhász T Varga A Csikkel‐Szolnoki J Nemcsók |
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| Institution: | 1. Department of Biochemistry , József Attila University , P.O. Box 533, Szeged, H‐6701, Hungary;2. Department of Biochemistry , József Attila University , P.O. Box 533, Szeged, H‐6701, Hungary;3. Bay Zoltán Foundation , Institute for Biotechnology , P.O. Box 2337, Szeged, H‐6701, Hungary;4. Department of Inorganic and Analytical Chemistry , József Attila University , P.O. Box 440, Szeged, H‐6701, Hungary |
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| Abstract: | Abstract Copper treatment, muscle and liver accumulate a great amount of copper ions. The higher concentration of copper ions in the organism caused an elevated level of metallothionein. Copper induced the synthesis of metallothionein, mostly in the livers. In gel chromatography heat stable low molecular weight protein certain coming from the destruction of high molecular weight proteins could be observed. On the effect of higher copper ion concentration in the liver, the level of the metallothionein bound to copper (as related to total protein bounded to copper) was decreased. This phenomenon shows the weaker affinity of apothionein to copper, compared to other proteins. Follows copper sulphate treatment, every measured blood serum parameter was changed. GOT activity rose to 130% and the GPT to 300% of control. LDH activity increased, too. According to this, the anaerobic way became preferred in glucose metabolism. On the effect of copper sulphate stress the blood serum glucose concentration was higher than the control value. |
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| Keywords: | metallothionein copper transaminase and fish |
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