Application of a LC–MS/MS method for multi-mycotoxin analysis in infant formula and milk-based products for young children commercialized in Southern Brazil |
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| Authors: | Karina M Tonon Geovana D Savi |
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| Institution: | 1. Nutrition Postgraduate Program, Federal University of Sao Paulo, S?o Paulo, Brazil;2. Iparque-Scientific and Technological Park, University of Southern Santa Catarina, Criciúma, Santa Catarina, Brazil;3. Food Science and Technology Department, Center of Agricultural Sciences, Federal University of Santa Catarina, Florianópolis, Santa Catarina, Brazil |
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| Abstract: | ABSTRACTAn analytical method based on liquid chromatography–tandem mass spectrometry (LC–MS/MS) was validated and applied for the analysis of aflatoxin M1 (AFM1), ochratoxin A (OTA) and deoxynivalenol (DON) in infant formula and milk-based products for young children commercialized in Brazil. A total of 38 samples were evaluated, including 12 infant formula, 14 follow-on formula and 12 samples of milk-based products. AFM1 was detected in 12 (32%) samples, and seven (18%) samples contained AFM1 levels above the method limit of quantification in a concentration range between 0.013 and 0.067 ng mL?1 (0.026 ± 0.019). Two samples of milk-based products exceeded the maximum level (ML) fixed by the European Union for AFM1 in baby foods, however, all samples were in agreement with the levels established by the Brazilian regulation. OTA and DON were not detected in any of the analyzed samples. |
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| Keywords: | Mycotoxins aflatoxin M1 ochratoxin A deoxynivalenol infant formula infant milk baby food LC–MS/MS |
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