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Biological evaluation of SZI‐121, a new miticide
Authors:László Pap  Janis Hajimichael  Edit Bleicher
Institution:AGCHEM Pesticide Development Department , CHINOIN Pharmaceutical and Chemical Works Co. Ltd , P.O.B. 49, Budapest, H‐1780, Hungary
Abstract:Abstract

A large number of tetrazine analogues were synthetised and tested as miticides. A comprehensive screening system was applied to recognise some effects important in terms of field performance. A promising new substance, coded as SZI‐121 was choosen for further development. It proved to be about four‐times more active as an ovicide (LC50=0.05 ppm) than the reference clofentezine, when administered to the eggs directly (LC50=0.23 ppm). In contrast to clofentezine which has solely a contact mode of action, SZI‐121 has excelent translaminar activity acting on already laid eggs (LC50= 18.66 ppm) or those in females feeding on the opposite, non‐treated side of the leaf (LC50=5.11 ppm). High toxicity of SZI‐121 to the chrysalis form (LC50=0.39 ppm) was also observed. The field rate of SZI‐121 is 60–100 g a.i./ha against a wide range of phytophagous mites including European red mite (Panonychus ulmi), two spotted spider mite (Tetranychus urticae), grape leaf rust mite (Calepitrimerus vitis), vine leaf blister mite (Colomerus vitis), apple leaf rust mite (Aculus schlechtendali), stone fruit leaf rust mite (Vasates fockeui). Because it stops the development of mites in egg and chrysalis forms simultaneously, SZI‐121 can be used independently from actual development stages of mites during the whole season as the field trials demonstrated. These characteristics permit SZI‐121 to be easily fitted into integrated pest management.
Keywords:flufenzine  miticide  translaminar and transovarian activity
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