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Determination of Oxidative Metabolism in Collembolan Proisotoma minuta (Tullberg)
Authors:EUN-KEE PARK  EDITH M LEES
Institution:1. Department of Entomology and Cancer Research Center , University of California , Davis, California, USA;2. Department of Agricultural Chemistry and Soil Science , University of Sydney , New South Wales, Australia
Abstract:

An oxidative metabolism of Collembolan Proisotoma minuta was determined with a model compound of aldrin and dieldrin in this paper. The seven-day LD50 values for aldrin, dieldrin, and piperonyl butoxide in salt solution were 0.496, 0.367, and 8.346 mg L?1, respectively. When P. minuta were exposed to aldrin, dieldrin was the sole metabolite. The conversion of aldrin to dieldrin was known to be catalyzed by P450 monooxygenases system. It has been shown that the synergist piperonyl butoxide inhibited the metabolism of aldrin in P. minuta.
Keywords:Collembola  Proisotoma minuta  Toxicity  Metabolism  Aldrin  
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