Curvularin from Penicillium baradicum baghdadi NRRL 3754, and biological effects |
| |
| Authors: | R F Vesonder A Ciegler D Fennell L W Tjarks A H Jensen |
| |
| Institution: | 1. Agricultural Research Service, U.S. Department of Agriculture , Northern Regional Research Center , Peoria, Illinois, 61604;2. Department of Animal Science , University of Illinois , Urbana, Illinois, 61801 |
| |
| Abstract: | Abstract Curvularin, a fungal metabolite similar in chemical structure to zearalenone, a potent estrogen, was tested for its estrogenic effects to gilts. No estrogenicity was observed to 60 kg gilts after feeding curvularin per os at a rate of 10 mg per day for 5 days. Curvularin was also nontoxic to mice and chick embryo. |
| |
| Keywords: | curvularin macrolide lactone estrogen |
|
|
