| 用平板双分子层脂膜模拟研究锌离子跨细胞膜的传递过程 |
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| 引用本文： | 朱宪,叶宇慧,孙当如. 用平板双分子层脂膜模拟研究锌离子跨细胞膜的传递过程[J]. 环境化学, 2005, 24(5): 558-561 |
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| 作者姓名： | 朱宪 叶宇慧 孙当如 |
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| 作者单位： | 上海大学环境与化学工程学院,上海,201800 |
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| 基金项目： | 国家自然科学基金资助项目（批准号：20176026）. |
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| 摘 要： | 制备了氧化胆固醇-卵磷脂（脑磷脂）平板双分子层脂膜，研究了膜配方对双分子层脂膜的稳定性和离子传递性能的影响，得到了最佳制膜工艺，并建立了锌离子跨卵（脑）磷脂膜的吸附-扩散模型，其计算值与实验值基本吻合．
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| 关 键 词： | 双分子层脂膜 细胞膜 模拟膜 氧化胆固醇 锌离子 物质传递 双分子层 磷脂膜 传递过程 模拟研究 平板 传递性能 制膜工艺 |
| 收稿时间： | 2004-10-07 |
| 修稿时间： | 2004-10-07 |
PREPARATION OF PLANAR BILAYER LIPID MEMBRANES AND ITS APPLICATION FOR RESEARCH ON Zn2+ TRANSFER ACROSS BLM |
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| ZHU Xian,YE Yu-hui,SUN Dang-ru. PREPARATION OF PLANAR BILAYER LIPID MEMBRANES AND ITS APPLICATION FOR RESEARCH ON Zn2+ TRANSFER ACROSS BLM[J]. Environmental Chemistry, 2005, 24(5): 558-561 |
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| Authors: | ZHU Xian YE Yu-hui SUN Dang-ru |
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| Affiliation: | School of Environmental and Chemical Engineering, Shanghai University, Shanghai, 201800 |
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| Abstract: | The planar bilayer lipid membranes(BLM)comprised by oxidated cholesterol a nd lecithin / cephalin have been made , Its stability and its ion penetrating ab ility also have been researched . The optimal technics of making membrane was co nfirmed . The transport process of simulating zinc across the membranes was stud ied .Finally, the adsorption-diffuse model has been founded , the calculated va lue based on this model tallied basically with the experimental value . |
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| Keywords: | bilayer lipid membranes cell membranes simulation membranes oxidated cholesterol zinc ion mass transfer. |
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