| 水溶性CdTe量子点对斑马鱼胚胎发育的影响 |
| |
| 引用本文： | 黄凯,林匡飞,张卫,苗优娜,周啸宇,张雯,周鹏,陆强. 水溶性CdTe量子点对斑马鱼胚胎发育的影响[J]. 环境科学学报, 2011, 31(4): 854-859 |
| |
| 作者姓名： | 黄凯 林匡飞 张卫 苗优娜 周啸宇 张雯 周鹏 陆强 |
| |
| 作者单位： | 1. 国家环境保护化工过程环境风险评价与控制重点实验室(华东理工大学),上海,200237
2. 国家环境保护化工过程环境风险评价与控制重点实验室(华东理工大学),上海,200237;华东理工大学资源与环境工程学院,上海,200237 |
| |
| 基金项目： | 国家自然科学基金项目(No.40871223,40901148)；中央高校基本科研业务费专项资金资助(No.WB0911011) |
| |
| 摘 要： | 本试验以巯基乙酸 (TGA)作为稳定剂合成水溶性CdTe量子点，采用斑马鱼胚胎发育技术，观测0、1、25、50、100、200、300、400 nmol/L各浓度的水溶性CdTe量子点对斑马鱼胚胎发育的影响．记录胚胎发育过程中具有代表性的毒理学终点(自主运动频率、内心率、体长)．结果表明：在胚胎受精后120小时（hours post fertilization）CdTe量子点半数致死浓度（LC50）为185.9 nmol/L．CdTe量子点对斑马鱼胚胎24hpf时1min自主运动频率、48hpf时10s内心率、体长都存在剂量-效应关系．TGA-CdTe能引起斑马鱼胚胎发生各种中毒症状，如心包囊肿、卵黄囊肿、脊柱弯曲、体节减少、心率减慢、黑色素沉积少等异常现象．
|
| 关 键 词： | CdTe量子点；斑马鱼；胚胎发育；毒性 |
| 收稿时间： | 2010-07-11 |
| 修稿时间： | 2010-09-15 |
Toxicity of soluble CdTe quantum dots on embryonic development of zebrafish |
| |
| HUANG Kai,LIN Kuangfei,ZHANG Wei,MIAO Youn,ZHOU Xiaoyu,ZHANG Wen,ZHOU Peng and LU Qiang. Toxicity of soluble CdTe quantum dots on embryonic development of zebrafish[J]. Acta Scientiae Circumstantiae, 2011, 31(4): 854-859 |
| |
| Authors: | HUANG Kai LIN Kuangfei ZHANG Wei MIAO Youn ZHOU Xiaoyu ZHANG Wen ZHOU Peng LU Qiang |
| |
| Affiliation: | State Environmental Protection Key Laboratory of Environmental Risk Assessment and Control on Chemical Process(East China University of Science and Technology), Shanghai 200237,1. State Environmental Protection Key Laboratory of Environmental Risk Assessment and Control on Chemical Process(East China University of Science and Technology), Shanghai 200237; 2. School of Resources and Environmental Engineering, East China Universit,1. State Environmental Protection Key Laboratory of Environmental Risk Assessment and Control on Chemical Process(East China University of Science and Technology), Shanghai 200237; 2. School of Resources and Environmental Engineering, East China Universit,State Environmental Protection Key Laboratory of Environmental Risk Assessment and Control on Chemical Process(East China University of Science and Technology), Shanghai 200237,State Environmental Protection Key Laboratory of Environmental Risk Assessment and Control on Chemical Process(East China University of Science and Technology), Shanghai 200237,State Environmental Protection Key Laboratory of Environmental Risk Assessment and Control on Chemical Process(East China University of Science and Technology), Shanghai 200237,State Environmental Protection Key Laboratory of Environmental Risk Assessment and Control on Chemical Process(East China University of Science and Technology), Shanghai 200237 and State Environmental Protection Key Laboratory of Environmental Risk Assessment and Control on Chemical Process(East China University of Science and Technology), Shanghai 200237 |
| |
| Abstract: | |
| |
| Keywords: | CdTe quantum dots zebrafish (Danio rerio) embryo development toxicity |
| 本文献已被 万方数据 等数据库收录！ |
| 点击此处可从《环境科学学报》浏览原始摘要信息 |
|
点击此处可从《环境科学学报》下载全文 |
|
