Combined effects of selenium/mercury and selenium/copper on the cell population of the alga Dunaliella minuta

The type of interaction of selenium and mercury, and selenium and copper on the cell growth of the planktonic alga Dunaliella minuta Lerche has been studied. The results for the various selenium/mercury and selenium/copper ratios showed that: (a) although mercury and selenium inhibited the growth of D. minuta when added to its cultures separately at levels greater than their respective threshold concentrations, they had antagonistic effects towards each other when added simulataneously at the beginning of growth; prior exposure of the culture to either metal for 2 d did not alter this antagonistic action; (b) similar antagonism was observed in combinations of selenium and copper for cultures with and without prior exposure to either metal. The reasons for the Se/Hg and Se/Cu antagonism are unknown; several hypotheses concerning possible detoxification mechanisms are proposed.