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A case of partial sirenomelia and possible vitamin A teratogenesis |
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| Authors: | E Von Lennep N El Khazen G De Pierreux J J Amy F Rodesch N Van Regemorter |
| Institution: | 1. Departments of Obstetrics and Gynecology of the Free Universities of Brussels (U.L.B., V.U.B.) Hôpital Saint Pierre, Rue Haute. 322, B-1000 Brussels, Belgium;2. Departments of Genetics of the Free Universities of Brussels (U.L.B., V.U.B.) Hôpital Saint Pierre, Rue Haute, 322, B-1000 Brussels, Belgium |
| Abstract: | Prenatal echographical findings of a partial sirenomelic fetus are described. An attempt was made to terminate pregnancy by administration of prostaglandin F2a, but uterine rupture occurred. The teratogenic role of vitamin A ingested by the mother in the penconceptional period is discussed. |
| Keywords: | Teratogenesis Vitamin A Sirenomelia Caudal regression syndrome Prenatal diagnosis |