|
|||||
|
|
Duration of vaginal bleeding and trisomy at prenatal diagnosis |
|
| Authors: | R. H. Neugut A. Lustenberger A. Nicholas J. Kline D. Warburton |
| Affiliation: | 1. Department of Genetics and Devolopment, Columbia University, New York, NY 10032, U.S.A G. H. Sergievsky Center, Faculty of Medicine, Columbia University, New York, U.S.A School of Public Health, Division of Epidemiology, Columbia University, New York, U.S.A;2. Department of Genetics and Devolopment, Columbia University, New York, NY 10032, U.S.A;3. Department of Genetics and Devolopment, Columbia University, New York, NY 10032, U.S.A G. H. Sergievsky Center, Faculty of Medicine, Columbia University, New York, U.S.A;4. G. H. Sergievsky Center, Faculty of Medicine, Columbia University, New York, U.S.A School of Public Health, Division of Epidemiology, Columbia University, New York, U.S.A New York State Psychiatric Institute, New York, U.S.A |
| Abstract: | In the case-control study of 118 women with autosomal trisomy identified at prenatal diagnosis and their 442 karyotypically normal matched controls, we found that there was no overall association between risk of trisomy and the presence of vaginal bleeding during pregnancy. However, a lengthy duration of bleeding appears to predict increased risk of trisorny. |
| Keywords: | Trisomy Down syndrome bleeding |