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Sacrococcygeal teratoma: Prenatal diagnosis with elevated alphafetoprotein and acetylcholinesterase in amniotic fluid |
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| Authors: | Frederick Hecht Barbara Kaiser Hecht Daniel O'Keeffe |
| Institution: | 1. The Genetics and Cancer Research Center, Southwest Biomedical Research Institute, 123 East University Drive, Tempe, Arizona 85281, U.S.A.
Department of Zoology, Arizona State University, Tempe, Arizona, U.S.A.;2. Perinatal Medicine, Department of Obstetrics & Gynecology, Good Samaritan Hospital, Phoenix, Arizona 85062, U.S.A. |
| Abstract: | A sacrococcygeal teratoma was suspected by ultrasound examination at 24 weeks gestation. The amniotic fluid alphafetoprotein was markedly elevated, as was maternal serum AFP. Gel electrophoresis of amniotic fluid showed an acetylcholinesterase band. Labour began at 25 weeks gestation and the chromosomally normal male fetus was found to have a sacrococcygeal teratoma equal to three-quarters of the weight of the fetus. |
| Keywords: | KEY WORDS Sacrococcygeal teratoma Fetal ultrasonography Amniotic acetylcholinesterase |