Experiences with unexpected structural chromosome aberrations in prenatal diagnosis in a danish series |
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| Authors: | Lars O. Vejerslev Ursula Friedrich |
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| Affiliation: | 1. The John F. Kennedy Institute, DK-2600 Glostrup, Denmark;2. Institute of Human Genetics, Aarhus University, DK-8000 Aarhus C, Denmark |
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| Abstract: | The investigation of 5547 prenatal diagnoses showed 31 unexpected structural chromosome rearrangements. These included 3 Robertsonian translocations, 14 reciprocal translocations and 14 inversions. A11 were balanced, including 5 de novo rearrangements. In 3 of these cases an induced abortion was performed and in 2 cases children without detectable malformations were delivered. |
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| Keywords: | Prenatal chromosome examination De novo chromosome rearrangements |
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