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Immediate and unexplained fetal death during mid-trimester amniocentesis
Authors:Lawrence R Shapiro MD  Niecee Singer  Shlomo M Mannor
Institution:Departments of Pediatrics, Pathology and Obstetrics and Gynecology, Westchester County Medical Center and New York Medical College, Valhalla, New York

Genetics Laboratory, Letchworth Village Developmental Center, Thiells, New York, U.S.A.

Abstract:Immediate and unexplained fetal death during mid-trimester amniocentesis for prenatal diagnosis was found to be an uncommon though real phenomenon. A survey of programmes in the United States detected 5 cases from 7524 at 4 centres. Postmortem examination was not helpful and a neurogenic mechanism is postulated. Awareness of this phenomenon and routine pre- and post-amniocentesis ultrasound monitoring may clarify the actual prevalence and etiology.
Keywords:Amniocentesis  Immediate fetal death
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