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Distinguishing hygroma and amniotic fluid |
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| Authors: | David J H Brock Lilias Barron David Bedgood Charles Rodeck |
| Institution: | 1. Human Genetics Unit, University of Edinburgh, Western General Hospital, Edinburgh EH4 2XU, Scotland;2. Harris Birthright Research Centre for Fetal Medicine, Department of Obstetrics and Gynaecology, Kings College, London SE5 8RX, U.K. |
| Abstract: | Fluid from cystic hygromata can be distinguished from amniotic fluid by measurement of alkaline phosphatase (ALP) isoenzymes. The former has a serum-type ALP, made up largely of the liver/bone/kidney isoenzyme and virtually no intestinal isoenzyme. Second trimester amniotic fluid ALP contains approximately 80 per cent intestinal isoenzyme. |
| Keywords: | Hygromata Alkaline phosphatase Intestinal isoenzyme |