Light microscopic visualization of peroxisomes and plasmalogens in first trimester chorionic villi |
| |
| Authors: | Prof F Roels V Verdonck M Pauwels L de Catte W Lissens I Liebaers M Elleder |
| |
| Institution: | 1. Department of Human Anatomy, vrije Universiteit Brussel, Brussels, Belgium;2. Department of Gynecology and Obstetrics. Vrije Universiteit Brussel, Brussels, Belgium;3. Department of Medical Genetics, Vrije Universiteit Brussel, Brussels, Belgium;4. Department of Pathology, Charles University, Prague, CSSR |
| |
| Abstract: | Peroxisomes and their metabolites the plasmalogens were visualized in chorionic villi by quick and simple procedures. Villi were stained and mounted in toto, and can also be embedded. These methods may contribute to early prenatal diagnosis of peroxisomal disorders (Zellweger syndrome, neonatal adrenoleukodystrophy, infantile Refsum's disease a.o.). |
| |
| Keywords: | Chorionic villus Peroxisomes Plasmalogens Zellweger syndrome Refsum disease |
|
|
