Can oculocutaneous albinism be diagnosed prenatally?

A study of scalp and forearm skin biopsies from normally pigmented fetuses of gestational ages 16 to 28 weeks has indicated that prenatal diagnosis of albinism is a theoretical possibility. Pigment is not present in cells of the epidermis but can be found in hair follicles at the bulbous peg stage in the scalp only. Such hair follicles are present in the scalp as early as 16 weeks gestation. The findings indicate that prenatal diagnosis of albinism could be made on a scalp biopsy within the second trimester of pregnancy.