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New potential mammalian lignan metabolites of environmental phytoestrogens
Authors:Barbara Raffaelli  Eija Leppälä  Clément Chappuis  Kristiina Wähälä
Institution:(1) Department of Chemistry, Organic Chemistry Laboratory, University of Helsinki, P.O. Box 55, 00014 Helsinki, Finland
Abstract:Seven new dibenzylbutyrolactone and six new dibenzylbutanediol lignans were prepared to assist in the identification of a number of potential mammalian metabolites of the endocrine disrupting plant lignans syringaresinol and medioresinol, present in food.
Keywords:Lignans  Enterolignans  Synthesis  Metabolites  Endocrine disruptors  Phytoestrogens  Food
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