Bioactive properties of extracts from Australian dorid nudibranchs

Specimens of 21 species of dorid nudibranchs were collected off Queensland and New South Wales, Australia, in 1984, and extracts were assayed against a variety of test organisms (bacteria, fungi, crustacean nauplii, a fish and a mammal). Antimicrobial activity was present in extracts of 80% of the 21 species assayed and in each of the five families investigated (Chromodorididae, Aegeridae, Phyllidiidae, Dorididae, and Dendrodorididae). This result adds the families Aegeridae, Phyllidiidae and Dendrodorididae to those with species known to possess such activity. Extracts of 18 of the 21 species possessed ichthyotoxins. This result adds the families Aegeridae, Dorididae and Dendrodorididae to those with species known to possess such activity. Further, extracts of 10 species (of 13 species tested) were toxic to mice and two of these 10 were toxic to Artemia sp. nauplii.