The properties of emulsifiers that enhance the replication of viruses in cell cultures |
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| Authors: | Spencer H.S. Lee Kenneth R. Rozee Stephen H. Safe John F.S. Crocker |
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| Affiliation: | 1. Department of Microbiology, Halifax, Nova Scotia Canada;2. Department of Pediatrics, Halifax, Nova Scotia Canada;3. Faculty of Medicine, Halifax, Nova Scotia Canada;4. Izaak Walton Killam Hospital for Children Dalhousie University Halifax, Nova Scotia Canada;1. Department of Chemistry, University of Guelph Guelph, Ontario Canada |
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| Abstract: | Some of a variety of commercial emulsifiers were capable of enhancing the sensitivity of mammalian cells in culture to infection with several viruses. Those viruses which were enhanced in their replication were single-stranded RNA viruses whereas the double-stranded viruses tested were non-responders. In addition, some cells lines, as compared to others, responded in a more sensitive manner to the active emulsifiers. |
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