In vitro radical scavenging activity of two Columbian Magnoliaceae |
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Authors: | Miguel A Puertas M Ana M Mesa V Jairo A Sáez V |
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Institution: | (1) Laboratorio Química de Plantas Colombianas, Instituto de Química, Universidad de Antioquia, A.A. 1226, Medellín, Colombia |
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Abstract: | The recent interest in the conservation of the tropical forest is due, at least in part, to the potential economic and health
benefits that can be exploited from several plants. This report shows the in vitro antioxidant activity of some fractions
isolated from leaves of two Columbian Magnoliaceae, Talauma hernandezii G. Lozano-C and Dugandiodendron yarumalense Lozano. The activity was determined using the radical monocation 2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS·+)
and the stable free radical 2-2-diphenyl-1-picrylhydrazyl (DPPH·), as part of general biological screening of these plants.
The antioxidant capacity obtained from fractions was similar to those of α-tocopherol, tert-butylated hydroxyanisole (BHA), and ascorbic acid. The most active scavenger extract was the fraction 7 (TAA = 48.6 mmol
Trolox/kg extract and IC50 ≤ 0.01 kg extract/mmol DPPH); and the least active was the fraction 1 (TAA = 11.23 mmol Trolox/kg extract and IC50 = 0.21 kg extract/mmol DPPH) all of them isolated from D. yarumalense. These results suggest that these plants can be attractive as source of antioxidant compounds with the ability to reduce
radicals like ATBS and DPPH. |
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