Changes of Surface Properties of Yeast Cell Wall Under Exposure of Electromagnetic Field (40.68 MHz) and Action of Nystatin |
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Authors: | S I Voychuk E N Gromozova P M Lytvyn V S Podgorsky |
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Institution: | (1) Institute of Microbiology and Virology, NAS Ukraine, Zabolotny Str., 154, 03143 Kyiv, Ukraine;(2) Institute of Semiconductor Physics NAS Ukraine, Nauky Pr., 45, 03028 Kyiv, Ukraine;(3) Institute of Microbiology and Virology NAS Ukraine, Zabolotny Str., 154, 03143 Kyiv, Ukraine |
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Abstract: | Summary Changes of the surface properties were studied in the cell wall of the yeast Saccharomyces cerevisiae Y-517 under influence of the electromagnetic field (EMF) (40.68 MHz) and lethal doses of the fungicidal antibiotic nystatin
(10 μg/106 cells). Atomic force microscopy was used to study surface topography and visco-elastic properties of the cell walls. Surface
carbohydrates were detected by lectins marked with gold with the help of the scanning electron microscope. Additional polysaccharide
layer appeared over cell surface after EMF exposure. We suggest that electromagnetic fields resulted in the change of the
cell surface, and, accordingly, the sensitivity of organisms to the antifungal antibiotics. |
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Keywords: | Saccharomyces cerevisiae cell wall electromagnetic field atomic force microscopy nystatin |
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