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Transfer rate of pesticide residues from medicinal plants in different types of extractive solutions
Authors:Alexandru Mihai Florea  Veronica Drumea  Roxana Andreea Nita  Adelina Bicu  Laura Olariu  Ligia Elena Dutu
Institution:1. Research &2. Development, Biotehnos SA, Otopeni, Romania;3. Faculty of Pharmacy, pharmacognosy, phytochemistry, and phytotherapy, Carol Davila University of Medicine and Pharmacy, Bucharest, Romaniaalexandru.florea@biotehnos.com;5. Faculty of Pharmacy, pharmacognosy, phytochemistry, and phytotherapy, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania
Abstract:Abstract

Starting from the suspicion that the medicinal herbs may contain traces of pesticides and taking into account the risks of patients being exposed to contaminated products, the aim of this research was to evaluate the pesticide residues and the degree of their transfer (%) in three types of preparations (infusion, decoctionand cold maceration), for four medicinal plant species very often used in phytotherapy (Rosmarini folium, Menthae folium, Saturejae herba and Basilica herba). For each type of plant product, four samples were purchased from different manufacturers and they have been analyzed using gas chromatography- tandem mass spectrometry. One out of four samples of the same plant species contain at least one pesticide residue above the maximum level and shows a significant transfer of these residues in aqueous extractive solutions during extraction. The highest rate of pesticide transfer from medicinal plants was identified in infusions, recommended by many manufacturers.
Keywords:GC-MS/MS  pesticide residues  extractive solutions  transfer rate %  QuEChERS
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