Organic contaminants in the environment: Research progress and needs

An already large and rapidly increasing number of manmade organic contaminants is found to be present in environmental samples from around the world. However, the biological effects of many of these compounds are unknown. Traditional biological testing, albeit important, cannot be done on each chemical due to limitations of the available resources. Therefore, new avenues should be pursued to screen out the hazardous compounds for more intensive research. One of these avenues, quantitative structure-activity correlations, applies the existing knowledge to estimate the effects of other, structurally related compounds. In combination with a fast and cost-effective biological test, this method appears useful in solving both the existing backlog and future needs for information on the safety and environmental effects of new chemicals.