Biomarker responses associated with halogenated organic contaminants in northern fulmars (Fulmarus glacialis) breeding in the Canadian Arctic |
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Authors: | Braune Birgit M Trudeau Suzanne Jeffrey Deborah A Mallory Mark L |
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Institution: | a Environment Canada, National Wildlife Research Centre, Carleton University, Raven Road, Ottawa, Ontario, Canada K1A 0H3 b Bancroft, Ontario, Canada K0L 1C0 c Environment Canada, Box 1714, Iqaluit, Nunavut, Canada X0A 0H0 |
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Abstract: | We examined relationships between hepatic concentrations of halogenated organic contaminants and ethoxyresorufin O-deethylase (EROD) activity and retinoid (vitamin A) concentrations in livers, as well as retinol and thyroid hormone (TT3, TT4) levels in blood plasma, of northern fulmars at two breeding colonies in the Canadian High Arctic. Biomarker levels or responses did not differ significantly between males and females at either colony, nor was there any significant difference between colonies. No significant relationships were found between thyroid hormone or hepatic retinoid concentrations and any of the dioxin-like compounds or their Toxic Equivalents (TEQs) although significant positive correlations were found with plasma retinol (p < 0.03). EROD activity was significantly correlated with hepatic dioxin-like compounds and their TEQs (p < 0.001) as well as total PCBs (p < 0.01), which suggests that EROD induction occurs in northern fulmars at environmentally-relevant concentrations. |
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Keywords: | Canadian Arctic Northern fulmar Organohalogens Biomarkers EROD |
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