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Reparaturdefiziente Saccharomyces-Stämme als Testorganismen |
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| Authors: | R. Shoja W. Laskowski R. Roth E. R. Lochmann |
| Affiliation: | 1. Institut für Biochemie und Molekularbiologie, Fachbereich Biologie, Freie Universit?t Berlin, Ehrenbergstra?e 26-28, D-W-1000, Berlin 33 2. Institut für Biophysik, Fachbereich Biologie, Freie Universit?t Berlin, Thielallee 63, D-W-1000, Berlin 33 3. Department of Biology, Illinois Institute of Technology, 60610, Chicago, Illinois, USA |
| Abstract: | The effects of 15 chemical compounds on cell multiplication ofSaccharomyces cerevisiae strains, both competent or defect in DNA repair, were studied as to standard tests to assess the toxicity of chemical compounds in the environment. The effects of 8-MOP and UVA as well as Thiopyronine and visible light were also investigated. The results show that it is possible to evaluate chemical compounds damaging DNA by comparing the response of the above mentioned strains. |
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