Bioaccessibility of polychlorinated biphenyls in workplace dust and its implication for risk assessment |
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| Authors: | Yuan Kang Yi Yin Yubon Man Laisheng Li Qiuyun Zhang Lixuan Zeng Jiwen Luo Ming Hung Wong |
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| Institution: | 1. School of Chemistry & Environment, South China Normal University, Guangdong Technology Research Center for Ecological Management and Remediation of Urban Water System, Higher Education Mega Center, Guangzhou 510006, People’s Republic of China;2. Croucher Institute for Environmental Sciences and Department of Biology, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China;3. Pearl River Fisheries Research Institute, Chinese Academy of Fishery Sciences, Key Laboratory of Tropical & Subtropical Fishery Resource Application & Cultivation, Ministry of Agriculture, Guangzhou 510380, People’s Republic of China |
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| Abstract: | Human exposure to bioaccessible PCBs via indoor dust is limited around the world. In the present study, the workplace dust sample from commercial office, hospital, secondary school, shopping mall, electronic factory and manufacturing plant were collected from Hong Kong for PCBs analyses. Total PCBs concentrations ranged from 46.8 to 249 ng g−1, with a median of 107 ng g−1. Manufacturing plant showed the highest concentration among all of sampling sites. PCB 77 was found as the dominant congeners. The bioaccessibility of PCBs in small intestinal juice ranging from 8.3% to 26.0% was significantly higher than that in gastric condition, ranging from 4.8% to 12.4%. In addition, significant negative correlations (p < 0.05) were observed between KOW and bioaccessibility for all workplace dust samples. Risk assessment indicated that the averaged daily dose of dioxin-like PCBs via non-dietary intake of workplace dust, considering the bioaccessibility of PCBs, were much lower than the TDI of dioxins (2.3 pg WHO-TEQ kg bw−1 d−1) established by Joint FAO/WHO Expert Committee on Food Additives. |
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| Keywords: | PCBs Workplace dust Bioaccessibility Risk Assessment |
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