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Health risk assessment of heavy metal intake due to fish consumption in the Sistan region,Iran
Authors:Mohammad Miri  Elham Akbari  Abdeltif Amrane  Seyed Javad Jafari  Hadi Eslami  Edris Hoseinzadeh  Mansur Zarrabi  Javad Salimi  Mohsen Sayyad-Arbabi  Mahmoud Taghavi
Institution:1.Department of Environmental Health Engineering, School of Public Health,Sabzevar University of Medical Sciences,Sabzevar,Iran;2.Department of Environmental Health Engineering,Zabol University of Medical Sciences,Zabol,Iran;3.Ecole Nationale Supérieure de Chimie de Rennes, CNRS, UMR 6226,Rennes Cedex 7,France;4.Department of Environmental Health Engineering, School of Public Health,Urmia University of Medical Sciences,Urmia,Iran;5.Department of Environmental Health Engineering, School of Public Health,Rafsanjan University of Medical Sciences,Rafsanjan,Iran;6.Young Researchers & Elite Club,Hamedan Branch, Islamic Azad University,Hamedan,Iran;7.Department of Environmental Health Engineering, Faculty of Health,Alborz University of Medical Sciences,Karaj,Iran;8.Department of Environmental Health Engineering,Torbat-e Heydariyeh University of Medical Sciences,Torbat-e Hydariyeh,Iran;9.Department of Environmental Health Engineering,Gonabad University of Medical Sciences,Gonabad,Iran
Abstract:The heavy metal (Pb, Cd, Cr, and Ni) content of a fish species consumed by the Sistan population and its associated health risk factors were investigated. The mean concentrations of Pb, Cd, and Cr were slightly higher than the standard levels. The Ni content of fish was below the maximum guideline proposed by the US Food and Drug Administration (USFDA). The average estimated weekly intake was significantly below the provisional tolerable intake based on the FAO and WHO standards for all studied metals. The target hazard quotients (THQ) of all metals were below 1, showing an absence of health hazard for the population of Sistan. The combined target hazard quotient for the considered metals was 26.94 × 10?3. The cancer risk factor for Pb (1.57 × 10?7) was below the acceptable lifetime carcinogenic risk (10?5). The results of this study reveal an almost safe level of Pb, Cd, Cr, and Ni contents in the fish consumed by the Sistan population.
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