A simple method for estimating dermal absorption of chemicals in water |
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| Authors: | Stephen L Brown and James E Rossi |
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| Institution: | ENVIRON Corporation 1000 Potomac Street, Washington, DC 20007, USA |
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| Abstract: | A semiempirical mathematical model is proposed for estimating the dermal absorption of chemicals from dilute aqueous solutions, such as bath water. Absorption depends on the concentration of the chemical in water, the area of skin exposed, the time of exposure, and a permeation coefficient that depends importantly on the relative solubility of the material in lipids and water, among other factors not so easily modeled. |
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| Keywords: | Absorption dermal skin chemicals water dilute aqueous solutions model |
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