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A simple method for estimating dermal absorption of chemicals in water
Authors:Stephen L. Brown and James E. Rossi
Affiliation:

ENVIRON Corporation 1000 Potomac Street, Washington, DC 20007, USA

Abstract:A semiempirical mathematical model is proposed for estimating the dermal absorption of chemicals from dilute aqueous solutions, such as bath water. Absorption depends on the concentration of the chemical in water, the area of skin exposed, the time of exposure, and a permeation coefficient that depends importantly on the relative solubility of the material in lipids and water, among other factors not so easily modeled.
Keywords:Absorption   dermal   skin   chemicals   water   dilute aqueous solutions   model
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