Some heterocyclic aromatic compounds are Ah receptor agonists in the DR-CALUX assay and the EROD assay with RTL-W1 cells |
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| Authors: | Gunnar Hinger Markus Brinkmann Kerstin Bluhm Anne Sagner Helena Takner Adolf Eisenträger Thomas Braunbeck Magnus Engwall Andreas Tiehm Henner Hollert |
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| Institution: | 1.Department of Ecosystem Analysis, Institute for Environmental Research,RWTH Aachen University,Aachen,Germany;2.Department of Environmental Biotechnology,Water Technology Center,Karlsruhe,Germany;3.Department of Natural Science, Man-Technology-Environment Research Centre (MTM),University of ?rebro,?rebro,Sweden;4.Federal Environment Agency, Dept. IV 2: Pharmaceuticals, Chemicals, Experimental Studies, in Div. IV: Chemical Safety,Dessau,Germany;5.Aquatic Toxicology and Ecology Section, Department of Zoology,University of Heidelberg,Heidelberg,Germany;6.Institute of Hygiene and Environmental Medicine, Medical Faculty,RWTH Aachen University,Aachen,Germany |
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| Abstract: | Purpose Heterocyclic aromatic compounds containing nitrogen, sulfur, or oxygen heteroatoms (NSO-HET) have been detected in air, soil,
marine, and freshwater systems. However, only few publications are available investigating NSO-HET using in vitro bioassays.
To support better characterization of environmental samples, selected NSO-HET were screened for dioxin-like activity in two
bioassays. |
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