Incorporation of inositol hexaphosphate into intact red blood cells |
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Authors: | Claude Nicolau Klaus Gersonde |
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Institution: | 1. Institut für Strahlenchemie im Max-Planck-Institut für Kohlenforschung, D-4330, Mülheim (Ruhr) 2. Abteilung Physiologische Chemie der Technischen Hochschule, D-5100, Aachen
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Abstract: | Fluid charged lipid vesicles loaded with an inositol hexaphosphate solution were used to transport this allosteric effector into human intact red blood cells. Rate and extent of uptake of the vesicles and of the effector by the red blood cells were measured as changes in the O2 half-saturation pressure and the 31P-NMR spectra of the intracellular inositol hexaphosphate-haemoglobin complex. |
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