Role of Enhancer of zeste on the Production of Drosophila melanogaster Pheromonal Hydrocarbons |
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Authors: | C Wicker-Thomas J -M Jallon |
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Institution: | (1) Université Paris-Sud, UMR8620, NAMC, Bat. 446, F-91405 Orsay Cédex, France e-mail: claude.wicker@ibaic.u-psud-fr, Fax: +33-1-69157726, FR |
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Abstract: | In a search for genes controlling the production of Drosophila melanogaster contact pheromones, the gene Enhancer of zeste E(z)] was found to be one player. Flies mutant for either the amorphic or the antimorphic allele of E(z) showed a similar hydrocarbon phenotype as those with the overlapping Df lxd
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deficiency: decreased amounts of total hydrocarbons and especially unsaturated ones in both sexes. The decrease in the level
of D. melanogaster female sex pheromone 7,11-heptacosadiene was dramatic and was correlated with an increase in 7-heptacosene. Females mutant
for a gain-of-function allele had increased amounts of total hydrocarbons with wild-type proportions of dienes. Thus the E(z) gene seems to affect hydrocarbon biosynthesis, especially its desaturation steps and even more so the female-specific desaturation
step transforming 7-monoenic fatty acids to 7,11-dienic ones and leading to female pheromones.
Received: 9 July 1999 / Accepted in revised form: 20 October 1999 |
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