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| 硝基芳烃对鲤鱼肝EROD活性影响的体外研究 | |
| 引用本文： | 王咏,王春霞,王子健,徐镜波.硝基芳烃对鲤鱼肝EROD活性影响的体外研究[J].环境科学,2001,22(4):120-122. |
| 作者姓名： | 王咏 王春霞 王子健 徐镜波 |
| 作者单位： | 1. 中国科学院生态环境研究中心环境水化学国家重点实验室,北京,100085;东北师范大学环境科学系,长春,130024 2. 东北师范大学环境科学系,长春,130024 3. 中国科学院生态环境研究中心环境水化学国家重点实验室,北京,100085 |
| 基金项目： | 国家自然科学基金项目(20037010);中国科学院项目(KZCX2-410). |
| 摘 要： | 在体外实验条件下,研究了9种硝基芳烃化合物对鲤鱼肝脏7-乙氧基异吩唑酮-脱乙基酶(EROD)的影响.结果表明,9种硝基芳烃化合物对EROD均有激活作用,在实验浓度范围内,EROD活性与浓度之间存在剂量-效应关系.实验发现苯环上同一位置的取代基不同或同一取代基在苯环上的位置不同,对EROD的激活程度的影响也不同. |
| 关 键 词： | 硝基芳烃 EROD 鲤鱼肝 环境毒理学 |
| 文章编号： | 0250-3301(2001)04-03-0120 |
| 收稿时间： | 2000/12/15 0:00:00 |
| 修稿时间： | 2000年12月15 |
EROD Induction in Liver Microsome of Carp(Cyprinus carpio) by Nitroaromatic Hydrocarbons in Vitro |
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| Wang Yong,Wang Chunxi,Wang Zijian and Xu Jingbo.EROD Induction in Liver Microsome of Carp(Cyprinus carpio) by Nitroaromatic Hydrocarbons in Vitro[J].Chinese Journal of Environmental Science,2001,22(4):120-122. | |
| Authors: | Wang Yong Wang Chunxi Wang Zijian and Xu Jingbo |
| Institution: | SKLEAC, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085. |
| Abstract: | Nine nitroaromatic hydrocarbons (NAHs) induction of EROD activity was investigated by an in vitro assay based on carp (Cyprinus carpio) hepatic microsome system All nine NAHs tested were found to induce the activity of EROD There was dose effect relationship between EROD activity and concentrations of NAHs It was found that EROD activity was different, when different groups substituted at the same position of benzene ring, or the same group was at different position of benzene ring |
| Keywords: | nitroaromtic hydrocarbon EROD liver of carp environmental toxicology |
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