几种渗透剂对阿维菌素的增效作用

采用甘蓝叶表法对5种渗透剂进行了筛选,在此基础上,采用幼虫浸渍法和叶片药膜法测定了JFC-2、TX-10和FP-T等3种渗透效果较好的渗透剂对阿维菌素的增效作用,及它们分别与阿维菌素混配后对甘蓝叶片渗透量的影响.结果表明,当阿维菌素药液中含有渗透剂的浓度分别为50、100、200mg/L时,渗透剂JFC-2对阿维菌素浸渍法毒力的增效比分别为1.54、1.74和2.16,叶片药膜法毒力的增效比分别为1.60、1.90和2.18;TX-10的浸渍法毒力增效比分别为1.47、1.70和1.97,叶片药膜法毒力的增效比分别为1.48、1.63和2.00;FP-T的浸渍法毒力增效比分别为1.56、1.59和1.78,叶片药膜法毒力的增效比分别为1.58、1.52和1.86;同时,上述3种渗透剂还可提高阿维菌素对甘蓝叶片的渗透速度,缩短渗透时间.图1表3参11

Permeability of Penetrating Agents and Their Synergism to Avermectin

The permeability of five penetrating agents was tested with cabbage leaf cuticle-penetrating method. Three effective agents were selected to study their synergism to avermectin using dipping method and contact & stomach method. The effect of penetrating agents on penetrating quantity was also discussed in this paper. The contact toxicity and stomach toxicity of avermectin mixed with JFC-2, TX-10 and fast-penetrating agent T (FP-T) at doses of 50, 100 and 200 mg/L in avermectin emulsion were tested. The synergism ratios of JFC-2 were 1.58, 1.73 and 2.18 of contact toxicity, and 1.60, 1.90 and 2.18 of contact & stomach toxicity; these of TX-10 were 1.47, 1.70 and 1.97 of contact toxicity, and 1.48, 1.63 and 2.00 of contact & stomach; and these of FP-T were 1.56, 1.59 and 1.78 of contact toxicity, and 1.58, 1.52 and 1.86 of contact & stomach, respectively. The penetrating quantity was greatly increased after JFC-2, TX-10 and FP-T were mixed into avermectin emulsion. The penetrating time was decreased by 50 % compared with CK. Fig 1, Tab 3, Ref 11