| 多溴联苯醚与四溴双酚A的生物代谢研究进展 |
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| 引用本文： | 沈梦楠, 高士祥. 多溴联苯醚与四溴双酚A的生物代谢研究进展[J]. 环境工程技术学报, 2015, 5(5): 418-423. doi: 10.3969/j.issn.1674-991X.2015.05.066 |
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| 作者姓名： | 沈梦楠 高士祥 |
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| 作者单位： | 1.松辽流域水环境教育部重点实验室,吉林建筑大学;;2.污染控制与资源化研究国家重点实验室, 南京大学 |
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| 摘 要： | 分析了生物体内多溴联苯醚（PBDEs）和四溴双酚A（TBBPA）的来源和分布，综述了PBDEs和TBBPA在生物体内发生还原代谢和氧化代谢的研究进展,从体内原位代谢和体外模拟代谢2个方面探讨了PBDEs和TBBPA的生物代谢机制、代谢途径及代谢中可能涉及的代谢酶，指出今后应进一步深入开展PBDEs和TBBPA的生物积累和代谢产物的定量分析的研究。
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| 关 键 词： | 多溴联苯醚（PBDEs） 四溴双酚A（TBBPA） 生物代谢转化 代谢酶 |
| 收稿时间： | 2015-03-30 |
| 修稿时间： | 2015-05-24 |
Biological Metabolic Transformation of Polybrominated Diphenyl Ethers and Tetrabromobisphenol A |
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| SHEN Meng-nan, GAO Shi-xiang. Biological Metabolic Transformation of Polybrominated Diphenyl Ethers and Tetrabromobisphenol A[J]. Journal of Environmental Engineering Technology, 2015, 5(5): 418-423. doi: 10.3969/j.issn.1674-991X.2015.05.066 |
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| Authors: | SHEN Meng-nan GAO Shi-xiang |
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| Affiliation: | 1. Key Laboratory of Songliao Aquatic Environment, Ministry of Education, Jilin Jianzhu University2. State Key Laboratory of Pollution Control and Resource Reuse;;2. School of the Environment, Nanjing University |
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| Abstract: | The distributions and sources of PBDEs and TBBPA in organism were analyzed, and the research progresses of reduction and oxidation metabolism of PBDEs and TBBPA in organisms were reviewed. The metabolism, pathways, and key enzymes involved in the biotransformation of them both in vivo and in vitro were explored. Directions for further studies on the bioaccumulation and biotransformation of PBDEs and TBBPA were proposed. |
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| Keywords: | polybrominated diphenyl ethers (PBDEs) tetrabromobisphenol A (TBBPA) biological metabolism metabolic enzymes |
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