Biotransformation of the fungicide pentachloronitrobenzene by |
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Authors: | Sharon E Murphy AnnaMarie Drotar Ray Fall |
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Institution: | Department of Chemistry and Cooperative Institute for Research in Environmental Sciences, Campus Box 215, University of Colorado, Boulder, Colorado 80309 USA |
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Abstract: | The protozoan, , metabolizes pentachloronitrobenzene to several products, including nitrite, pentachlorothioanisole and pentachloroaniline. The latter two metabolites were identified by gas chromatographymass spectrometry. Pentachlorothioanisole may be produced via a glutathione-dependent pathway, and two key enzymes of this pathway, glutathione transferase and thiol S-methyltransferase, have been detected in crude extracts of this microorganism. |
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