头孢中间体合成废水组成分析及主要污染物识别

为了识别头孢抗生素生产废水中的主要污染物,掌握其水质特点,对头孢抗生素中间体合成废水进行了物质组成分析。水样取自天津某头孢生产企业废水处理系统的进水和出水。采用气相色谱-质谱联用(GC-MS)技术对污染物进行检测,经色谱柱分离后将各组分的质谱图与NIST08数据库对比、定性,确定了样品预处理方法和GC-MS分析的条件。研究结果表明,头孢中间体合成废水中存在7大类30余种化合物,通过对比废水处理系统进出水组成,确定了含N多环和杂环类化合物为最难降解的污染物,为此类废水的物理强化预处理和深度处理提供了依据。

Composition analysis of cephalosporin intermediate plant effluent and preliminary identification of major organic pollutants

To determine the composition of organic pollutants in the cephalosporin synthesis wastewater, the gas chromatography-mass spectrometry (GC-MS) technology was used and the analytical method was optimized. The influent and effluent of the existing treatment system were sampled at a cephalosporin intermediate plant located in Tianjin. The organic matter was extracted from raw wastewater using dichloromethane. After concentration and purification, the samples were injected into the column for separation. The qualitative analysis was made by comparing the obtained mass spectrograms to NIST08 database. Over 30 kinds of organic pollutants were identified and the chemical structure and abundance information of each molecule were provided. After further classification of the listed components, it is concluded that heterocycles and nitrogen-containing polycycles are the most recalcitrant pollutants discharged by the cephalosporin intermediate plant which are supposed to be treated by additional physico-chemical process.