广东一饮用水源地河流沉积物及鱼体中氟喹诺酮类(FQs)抗生素残留特征研究

本研究对广东一饮用水源保护区的河流氟喹诺酮类(Fluoroquinolones,FQs)抗生素进行分析.采用高效液相色谱法定性定量分析9个沉积物样品和5种鱼肉及1种鱼内脏中3种FQs—诺氟沙星(Norfloxacin,NOR)、环丙沙星(Ciprofloxacin,CIP)、恩诺沙星(Enrofloxacin,ENR)的残留特征,并与沉积物中有机质、总氮、总磷进行Person相关性分析.结果表明:河流沉积物各点平均值NORCIPENR,最大含量分别为:NOR248.25 ng·g-1,CIP 158.69 ng·g-1,ENR 56.81 ng·g-1;FQs和沉积物有机质、总磷相关系数平均为0.946、0.968(p0.01);5种鱼的鱼肉中FQs的含量可能高于或低于沉积物中FQs含量均值;鳙鱼内脏FQs含量是鱼肉中的3.21~9.53倍.研究结果对保障饮用水安全及水产品生态安全具有重要的意义.

Residues characteristics of fluoroquinolones (FQs) in the river sediments and fish tissues in a drinking water protection area of Guangdong Province

The objective of this investigation was to study fluoroquinolones (FQs) in a drinking water protection area in Guangdong Province. Analysis of the distribution and patterns of FQs-Norfloxacin (NOR), Ciprofloxacin (CIP) and Enrofloxacin (ENR) residues in sediments from nine sample sites and in muscle tissues from five kinds of fish species and one kind of fish viscera were carried out by high performance liquid chromatography (HPLC) qualitatively and quantitatively. Pearson correlation analysis was used to analyze the relationship between the physio-chemical properties and FQs in the sediment. The results showed that the average concentrations of FQs samples were ranked as the following order:NOR> CIP> ENR, and the maximum concentration was 248.25 ng·g^-1 (NOR), 158.69 ng·g^-1 (CIP) and 56.81 ng·g^-1 (ENR), respectively. The concentrations of FQs exhibited a positive correlation with sediment organic content and total phosphorus, with the average correlation coefficient of 0.946 and 0.968 (p<0.01), respectively. Mean concentrations of FQs in fish muscle can be either higher or lower than those in the sediment. FQs detected in viscera was 3.21~9.53 times those in the muscle of hypophthalmichthys nobilis. These results were of great practical significance in ensuring drinking water safety and ecological safety of aquatic products.