Assessment of DDT, DDE, and 1-hydroxypyrene levels in blood and urine samples in children from Chiapas Mexico |
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| Authors: | Rebeca I Mart??nez-salinas Iv??n N P??rez-Maldonado Lilia E Batres-Esquivel Rogelio Flores-Ram??rez Fernando D??az-Barriga |
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| Institution: | Departamento Toxicología Ambiental, Facultad de Medicina, Universidad Autónoma de San Luis Potosí, Avenida Venustiano Carranza 2405, 78210, San Luis Potosí, S.L.P., Mexico. |
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| Abstract: | Purpose The aim of this study was assess co-exposure to DDT, DDE (main DDT metabolite), and PAHs (1-hydroxypyrene) in areas where biomass is used to cook and to heat homes and where DDT was used to combat malaria transmission. Methods During 2009, we analyzed a total of 190 blood and urine samples from children living in six communities in Mexico. Quantitative analyses of DDT and DDE were performed using gas chromatography coupled with mass spectrometry. Analyses of 1-hydroxypyrene were performed by HPLC using a fluorescence detector. Results In this work, we found high levels of DDT and its principal metabolite (DDE) in the blood of children living in four communities in Chiapas located in the southeastern region of Mexico (range, Conclusion This study demonstrates that children in these communities were exposed to DDT and its metabolites, and to other contaminants generated by the combustion of firewood. Therefore, the complex mixture studied in this study (PAHs and DDT/DDE) requires further research. |
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