| 水华蓝藻细胞提取物对实验鼠毒理效应研究进展 |
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| 引用本文： | 秦文弟,杨柳燕. 水华蓝藻细胞提取物对实验鼠毒理效应研究进展[J]. 环境科学文摘, 2011, 0(5) |
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| 作者姓名： | 秦文弟 杨柳燕 |
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| 作者单位： | 污染控制与资源化研究国家重点实验室南京大学环境学院; |
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| 基金项目： | 国家重点基础研究发展计划(973)项目(2008CB418102) |
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| 摘 要： | 蓝藻暴发引发的水华造成了严重的生态灾难和健康危害,蓝藻水华污染因其已成为全球性的环境问题而受到关注。蓝藻产生的藻毒素具有潜在致癌作用,与多种消化道肿瘤的发病率升高相关,其毒理学效应及其健康危害性更是学术界研究和关注的热点。水华蓝藻细胞提取物较之纯藻毒素的毒理学效应有很大不同,研究水华蓝藻细胞提取物对哺乳动物的毒理学效应能为蓝藻水华的健康风险评估提供一定的理论依据。水华蓝藻细胞提取物对实验鼠产生的毒理学效应,如脏器细胞凋亡和对各脏器抗氧化酶防御系统的损害;水华蓝藻细胞提取物对实验鼠遗传毒性和促癌或致癌作用研究是目前研究的热点和难点问题。
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| 关 键 词： | 蓝藻细胞提取物 实验鼠 毒理效应 健康风险 |
Toxicological Effects of Cyanobacterial Cell Extract on Muridae |
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| QIN Wen-di,YANG Liu-yan State Key Laboratory of Pollution Control , Resource Reuse,School of the Environment,Nanjing University,Nanjing ,China. Toxicological Effects of Cyanobacterial Cell Extract on Muridae[J]. Abstracts of Environmental Sciences, 2011, 0(5) |
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| Authors: | QIN Wen-di YANG Liu-yan State Key Laboratory of Pollution Control Resource Reuse School of the Environment Nanjing University Nanjing China |
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| Affiliation: | QIN Wen-di,YANG Liu-yan State Key Laboratory of Pollution Control and Resource Reuse,School of the Environment,Nanjing University,Nanjing 210093,China |
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| Abstract: | Cyanobacterial bloom causes serious ecological disasters and health hazards,and had become a global environmental problem.There was an association between increased incidence of various digestive tract tumor and cyanobacterial toxins produced by occurrence of cyanobacterial bloom and its toxicological effects and health risk had become a focus of academic research.The toxicological effects of cyanobacterial cell extract were different from pure microcystin.The study on toxicological effects of cyanobacteria... |
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| Keywords: | cyanobacterial cell extract muridae toxicological effect health risk |
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