环渤海区域典型河流下游水体中抗生素赋存状况及风险评估

利用高效液相色谱-串联质谱法分析了环渤海区域典型河流下游水体中6类58种抗生素的赋存特征,采用生态风险模型和人类健康风险模型分别评估了抗生素对生态和人体的健康风险.结果显示:环渤海区域4大典型河流(小凌河、滦河、黄河和大辽河)下游水体中有6类50种抗生素被检出,青霉素G浓度水平最高,最高浓度为353.13ng/L.β-...

Occurrences and risk assessment of antibiotics in water bodies of major rivers in Bohai Rim Basin

This study was conducted to characterize the occurrences and accumulation of antibiotics in surface water of each river's downstream in Bohai Rim Basin and to evaluate their ecological risk and human health risk. The results indicate that 50 antibiotics falling into 6 categories were detected in the lower reaches of four major rivers (Xiaoling, Luanhe, Yellow River and Daliao) in Bohai Rim Basin. Off all kinds of antibiotics, β-Ls, MLs and QNs were dominant in those waterbodies of the basin, of which the concentration of Penicillin G was the highest, up to 353.13ng/L. Compared with other rivers in China, The concentration of antibiotics ranged from 124.50ng/L to 489.16ng/L whose average concentration over the study area was rated at a moderate pollution level, but higher than that in other rivers of China. The accumulation level of different rivers was rated in the order as: Xiaoling River>Daliao River>Luanhe River>Yellow River. In addition, amoxicillin, anhydroerythromycin and erythromycin presented higher ecological risk to sensitive aquatic species than did tetracycline, oxytetracycline, enrofloxacin, ofloxacin and cinoxacin which were evaluated at a moderate ecological risk. According to the threshold of the human health risk value of target antibiotics (2.53×10^-7~6.79×10^-3), the pollution level of the antibiotics in the Bohai Rim Basin did not become a health threat to people yet.