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硫醇式磷酰胺类杀虫剂对大鼠红细胞膜脂质过氧化的影响
引用本文:丁志鸣,刘毓谷. 硫醇式磷酰胺类杀虫剂对大鼠红细胞膜脂质过氧化的影响[J]. 环境科学学报, 1987, 7(3): 361-366
作者姓名:丁志鸣  刘毓谷
作者单位:同济医科大学环境毒理研究室(丁志鸣),同济医科大学环境毒理研究室(刘毓谷)
摘    要:研究了三种新合成的硫醇式磷酰胺类杀虫剂对大鼠红细胞膜丙二醛含量及高分子蛋白形成的影响,分析了两者之间的相互关系。结果表明,这三种杀虫剂对膜丙二醛含量无影响,但是FPP可以引起高分子蛋白的形成,而高分子蛋白形成可以使正常膜蛋白成份发生改变。

关 键 词:杀虫剂  硫醇式磷酰胺  脂质过氧化  有机磷  杀虫剂
收稿时间:1986-10-11

EFFECTS OF PHOSPHORAMIDOTHIOLATE PESTICIDES ON THE LIPID PEROXIDATION OF ERYTHROCYTE MEMBRANE
Ding Zhiming and Liu Yugu. EFFECTS OF PHOSPHORAMIDOTHIOLATE PESTICIDES ON THE LIPID PEROXIDATION OF ERYTHROCYTE MEMBRANE[J]. Acta Scientiae Circumstantiae, 1987, 7(3): 361-366
Authors:Ding Zhiming and Liu Yugu
Affiliation:Institute of Environmental Toxicology, Tongji Medical University and Institute of Environmental Toxicology, Tongji Medical University
Abstract:The effects of phosphoramidothiolate pesticides on the lipid peroxi-dation of rat erythrocyte membrane were studied by analysing the content of malonaldehyde and the formation of high molecular weight protein. The pesticides investigated did not influence the content of malonaldehyde of membrane, but led to the formation of high molecular weight protein. It was also found that the formation of high molecular weight protein changed the normal protein component of membrane.
Keywords:pesticide  phosphoramidothiolate  lipid peroxidation  organophosphorate.
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