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Genotoxic Effect of Phenol on the Cells of Onion (Allium cepa) Roots |
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| Authors: | Gisele Pigatto Regildo Marcio Gon alves da Silv Gian Luigi Mariottini Vanessa Marques de Oliveir Mauri Sergio Alves Palma and Attilio Converti |
| Institution: | 1. Department of Pharmaceutical and Biochemical Technology, Universidade de Sao Paulo, Sao Paulo, SP, Brasil 2. Department of Civil, Chemical and Environmental Engineering, University of Genoa, Genova, Italy;Department of Biology, Universidade Estadual Paulista, Assis, SP, Brasil;Department of Earth, Environment and Life Sciences, University of Genoa, Genova, Italy;Department of Biology, Universidade Estadual Paulista, Assis, SP, Brasil;Department of Pharmaceutical and Biochemical Technology, Universidade de Sao Paulo, Sao Paulo, SP, Brasil;Department of Civil, Chemical and Environmental Engineering, University of Genoa, Genova, Italy |
| Abstract: | The roots of onion (Allium cepa ) stand out for having cells with large size and small number of chromosomes. These characteristics make them useful in bioassays for the measurement of a variety of cytogenetic and morphological parameters, in which they can be used as toxicity indicators of the induction and formation of micronuclei and chromosomal aberrations. Based on this background, the potential genotoxic effect of phenol concentration on cells of A. cepa roots was investigated either in terms of induced aberrations or micronuclei formation. The results demonstrated that the higher the concentration of phenol, the higher the incidence of abnormalities, thus confirming the genotoxicity of this pollutant. |
| Keywords: | phenol Allium cepa toxicity genotoxicity roots |
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