| A human embryonic stem cell-based in vitro model revealed that ultrafine carbon particles may cause skin inflammation and psoriasis |
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| 作者姓名： | Zhanwen Cheng Xiaoxing Liang Shaojun Liang Nuoya Yin Francesco Faiola |
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| 作者单位： | 1. State Key Laboratory of Environmental Chemistry and Ecotoxicology,Research Center for Eco-Environmental Sciences,Chinese Academy of Sciences;2. College of Resources and Environment,University of Chinese Academy of Sciences |
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| 基金项目： | We would also like to thank Dr;Wong Education Foundation;Zhanfen Qin for their help with the cryo-sections,and the K;Jinbo Li and Prof;This work was supported by the National Natural Science Foundation of China |
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| 摘 要： | Air pollution has been linked to many health issues,including skin conditions,especially in children.Among all the atmospheric pollutants,ultrafine particles have been deemed very dangerous since they can readily penetrate the lungs and skin,and be absorbed into the bloodstream.Here,we employed a human embryonic stem cell(h ESC)-based differentiation system towards keratinocytes,to test the effects of ultrafine carbon particles,which mimic ambient ultrafine particles,at environment related conce...
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| 收稿时间： | 2019/1/30 0:00:00 |
A human embryonic stem cell-based in vitro model revealed that ultrafine carbon particles may cause skin inflammation and psoriasis |
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| Zhanwen Cheng,Xiaoxing Liang,Shaojun Liang,Nuoya Yin,Francesco Faiola.A human embryonic stem cell-based in vitro model revealed that ultrafine carbon particles may cause skin inflammation and psoriasis[J].Journal of Environmental Sciences,2020,32(1):194-204. |
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| Authors: | Zhanwen Cheng Xiaoxing Liang Shaojun Liang Nuoya Yin Francesco Faiola |
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| Institution: | State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China;College of Resources and Environment, University of Chinese Academy of Sciences, Beijing 100049, China;State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China;College of Resources and Environment, University of Chinese Academy of Sciences, Beijing 100049, China;State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China;College of Resources and Environment, University of Chinese Academy of Sciences, Beijing 100049, China;State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China;College of Resources and Environment, University of Chinese Academy of Sciences, Beijing 100049, China;State Key Laboratory of Environmental Chemistry and Ecotoxicology, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing 100085, China;College of Resources and Environment, University of Chinese Academy of Sciences, Beijing 100049, China |
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| Abstract: | |
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| Keywords: | Corresponding author Human embryonic stem cells (hESCs) Keratinocytes Ultrafine carbon particles Inflammation Psoriasis Developmental toxicity |
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