| 硫丹对草鱼乙酰胆碱酯酶及抗氧化酶活性的影响 |
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| 引用本文： | 武焕阳,OSCAR Ortegon,许莉佳,靳涛,彭开琴,丁诗华,李云.硫丹对草鱼乙酰胆碱酯酶及抗氧化酶活性的影响[J].生态环境,2011(10):1496-1502. |
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| 作者姓名： | 武焕阳 OSCAR Ortegon 许莉佳 靳涛 彭开琴 丁诗华 李云 |
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| 作者单位： | 西南大学动物科技学院;重庆市水产科学重点实验室; |
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| 基金项目： | 国家自然科学基金项目(30670226); 重庆市自然科学基金项目(CSTC,2007BB1373) |
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| 摘 要： | 研究了硫丹暴露对草鱼肝脏、肌肉抗氧化酶及脑乙酰胆碱酯酶活性的影响。结果表明,硫丹24 h暴露可诱导草鱼脑AChE活性,当暴露时间延长或质量浓度升高时,AChE活性表现为受抑制,120 h较高质量浓度组抑制率为41.8%和56.2%,抑制率与暴露时间呈良好的线性相关。硫丹暴露24 h后,草鱼肝脏及肌肉SOD、GSH-Px活性受到显著影响,表现出先诱导后缓慢降低的趋势,120 h后SOD活性显著低于对照组水平,GSH-Px活性与对照组无显著差异。在抗氧化酶受到影响的同时,鱼体脂质过氧化LPO程度不断上升,组织MDA含量逐渐增大,96 h达到最高值。硫丹可影响草鱼AChE及抗氧化酶活性,其变化可作为生物标志物,来评价化学污染物对水生动物的生物学效应。
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| 关 键 词： | 硫丹 草鱼 乙酰胆碱酯酶（AChE） 抗氧化酶 |
Effects of endosulfan on activities of acetylcholinesterase and antioxidant enzyme of Ctenopharyngodon idellus |
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| WU Huanyang,OSCAR Ortegon,XU Lijia,JIN Tao,PENG Kaiqin,DING Shihua,LI Yun, .College of Animal Science , Technology,Southwest University,Chongqing ,China,.Key Laboratory of Aquatic Science of Chongqing.Effects of endosulfan on activities of acetylcholinesterase and antioxidant enzyme of Ctenopharyngodon idellus[J].Ecology and Environmnet,2011(10):1496-1502. |
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| Authors: | WU Huanyang OSCAR Ortegon XU Lijia JIN Tao PENG Kaiqin DING Shihua LI Yun College of Animal Science Technology Southwest University Chongqing China Key Laboratory of Aquatic Science of Chongqing |
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| Institution: | WU Huanyang1,2,OSCAR Ortegon1,XU Lijia1,JIN Tao1,PENG Kaiqin1,DING Shihua1,LI Yun1,2 1.College of Animal Science and Technology,Southwest University,Chongqing 400715,China,2.Key Laboratory of Aquatic Science of Chongqing |
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| Abstract: | The effects of endosulfan exposure on the induction of oxidative stress and the alteration of AChE activities were studied in liver,muscle and brain samples from Ctenopharyngodon idellus.The results showed that the AChE activities of brain in Ctenopharyngodon idellus was stimulated after 24 h exposure.However,The activities of AChE were restrained when the exposure time and concentration was increased,and the inhibition rate was 41.8% and 56.2% in higher concentration groups after 120 h exposure,it showed a... |
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| Keywords: | endosulfan Ctenopharyngodon idellus acetylcholinesterases(AChE) antioxidant enzyme |
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