二种除草剂遗传毒性的研究

以黄鳝为试验材料,研究了艾割和使它隆二种除草剂对鱼类的致突变性。对经腹腔注射染毒上述二种除草剂的受试黄鳝,通过对其活体肾细胞染色体数目和形态的观察,分析其突变率。研究结果(经t检验)显示:艾割和使它隆二种除草剂分别在其试验最低受试剂量50mg/kg和8.0mg/kg即可引起黄鳝的染色体畸变。采用SOS/Umu显色试验研究,在SOS/Umu试验中,使它隆和艾割2个受试除草剂可以诱发SOS阳性反应,且呈明显的剂量-效应关系。试验表明这二种除草剂具有遗传毒性,应对这二种除草剂严加管控,避免其对环境的影响。

Study on Genetic Toxicity of Herbicides

The induced mutagenesis by herbicides such as argold and starane on Monopterus albus was observed and analysed.After injected with herbicides through the abdomen cavity,the kidney cells were used for chromosomal aberrations rate analysis by air-drying method.Results by T-test showed that the two kinds of herbicides could induce chromosomal aberrations even at the lowest injection dosage of 50mg/kg for argold and 8.0mg/kg for starane respectively.In the SOS/Umu chromotest,starane and argold could induce SOS reaction.Results indicated that the pesticides had mutation effects,with close relationship to the concentration.The two kinds of herbicides are suggested to be strictly controlled to prevent hazardousness to aquatic animal and the environment.