Prenatal diagnosis of osteogenesis imperfecta type III

Ultrasonographic and radiographic evaluation of a fetus at risk for osteogenesis imperfecta (O.I) type III was performed. Real-time ultrasound measurements at 15 weeks gestation were interpreted as normal, but at 20 and 22 weeks of gestation revealed marked shortening of the long bones and deformity of the femurs. The findings were confirmed by fetal radiography at 22 weeks gestation. Radiographic and histologic changes characteristic of O.I. were observed in the aborted fetus. Thus the antenatal manifestations of O.I. type III maybe severe enough to make prenatal diagnosis possible in the second trimester for families at risk for recurrence of this disorder.     

Listeriosis: A cause of non-immune hydrops fetalis

A case of prenatally diagnosed non-immune hydrops fetalis, that was later shown to be caused by listeriosis, is presented, and the clinical course, as well as the appropriate diagnostic and therapeutic procedures are described. We conclude, that listeriosis should be excluded, whenever a non-immune hydrops fetalis is associated with septicemia, influenza-like illness and fever of unknown origin.     

Bioenergy to mitigate for climate change and meet the needs of society,the economy and the environment

Changes towards environmental improvementsare becoming more politically acceptableglobally, especially in developedcountries. Society is slowly moving towardsseeking more sustainable productionmethods, waste minimisation, reduced airpollution from vehicles, distributed energygeneration, conservation of native forests,and reduction of greenhouse gas (GHG)emissions. Modern biomass, when used tosupply useful bioenergy services, has arole to play in each one of theseenvironmental drivers at both the large andsmall scales.This paper describes recent developments inbiomass supply and the technologies for itsconversion to bioenergy including biofuelsfor transport. It examines the economic,environmental and social benefits andidentifies barriers to bioenergy projectimplementation. Future opportunities forbiomass as a carbon (C) sink, a C offsetand a potential source of renewablehydrogen are discussed.Whether or not a bioenergy project iseconomically viable, as well as being trulyrenewable, sustainable and environmentallysound, is determined mainly by the sourceof biomass. The social benefits from usingbiomass are also valuable, though they areoften not clearly presented when proposingnew bioenergy projects or conductinganalyses of existing plants. Employmentrates per MWh or per GJ exceed those whenusing fossil fuel supplies to provide thesame energy service. `Ownership' bystakeholders and local communities at anearly stage in the development process isthe key to successful project developmentin order to share the benefits. Bioenergyhas a significant global role to play inthe mitigation of atmospheric GHG concentrations.     

An experiment on the economic value of visibility

This paper reports on the development and application of an iterative bidding technique to examine proposed visibility reductions in the Four Corners Region of the southwest United States. The iterative bidding technique is a method to elicit honest bids for “goods” not priced in formal markets. Four issues associated with direct revelation of preferences for environmental goods are explored: (1) the establishment of linkages between the physical parameters of visibility and representation of the “good” called visibility to individuals for valuation purposes; (2) a systematic test for both observed and induced biases associated with the interative bidding technique; (3) replication of the results of previous experiments; and (4) reporting of empirical divergences between compensating and equivalent surplus measures of consumer surplus.     

An Air Quality Data Analysis System for Interrelating Effects,Standards, and Needed Source Reductions: Part 11. A Lognormal Model Relating Human Lung Function Decrease to O3 Exposure

Forced expiratory volume in 1 second (FEV1) was measured in 21 men exercising while exposed to four O₃ concentrations (0.0,0.08,0.10, and 0.12 ppm). A lognormal multiple linear regression model was fitted to their mean FEV1 measurements to predict FEV1 percent decrease as a function of O₃ concentration and exposure duration. The exercise level used was probably comparable to heavy manual labor. The longest O₃, exposure studied was 6 h. Extrapolating cautiously to an 8-h workday of heavy manual labor, the model predicts that O3 concentrations of 0.08, 0.10, and 0.12 ppm would decrease FEV1 by 9,15, and 20 percent, respectively.     

Screening pesticides for their ability to damage bacterial DNA

Abstract

Twenty‐six pesticides and pesticide degradation products were screened (125 μg ‐ 2000 μg) for their ability to induce unrepairable damage to bacterial DNA. Three repair test systems were utilized in this study, the Salmonella typhimurium (TA1538/TA1978), the E. coli K‐12 (Pol A₁ ⁺/Pol^‐ ₁) and the E. coli WP₂ (WP₂, WP₂ uvrA, WP67, CM611 and CM571). Aldicarb (1000 μg), benomyl (250 μg), 2‐aminobenzimidazole (2000 μg), captan (125 μg), fenazalor (500 μg), 5,6‐dichloro‐2‐trifluoromethylbenzimida‐zole (NC‐2983) (250 μg), isothymol (250 μg), maleic hydrazide(1000 μg), pentachloronitrobenzene (1000 μg) were DNA‐damaglng to one or more bacterial test systems. Isothymol and NC‐2983 affected all three test systems. Chlorinated hydrocarbon insec ticides, some being recognized as carcinogens, did not: produce a zone of inhibition in any of the tester strains possibly due to their poor solubility and diffusion in the agar overlay. It was concluded that these tests can be performed along with bacterial reversion tests to complement each other as short‐term screening tests for potential carcinogens and mutagens.