Exergy analysis of the transcritical N2O refrigeration cycle with a vortex tube

In this article, a comparative study is presented for the transcritical cycle with expansion valve (TCEV) and transcritical cycle with vortex tube (TCVT) mainly based on the second law of thermodynamics. Natural refrigerant nitrous oxide (N₂O) is used in both the cycles for analysis. The evaporator and gas cooler temperatures are varied from ?55°C to 5°C and 35°C to 60°C, respectively. The effects of various operating and design parameters on the optimum heat rejection pressure, coefficient of performance (COP), exergy loss (irreversibility), and the exergetic efficiency are studied. Exergy analysis of each component in TCEV and TCVT is performed to identify the amount and locations of irreversibility. It is observed that the use of the vortex tube in place of the expansion valve reduces the total exergy losses and increases the exergetic efficiency as well as COP. The exergetic efficiency and COP of the TCVT are on average 10–12% higher compared to TCEV for the considered operating conditions. The computed values of the exergetic efficiency for TCVT using refrigerant N₂O are the highest at an evaporator temperature of ?55°C, and the corresponding values of exergetic efficiency and exergy losses varies between 25.35% and 15.67% and between 74.65% and 84.33%, respectively. However, COP at the same evaporator temperature of ?55°C varies between 0.83 and 0.51. Furthermore, the optimum heat rejection pressure in TCVT is lower compared to that in TCEV. The results offer significant help for the optimum design and operating conditions of TCVT with refrigerant N₂O.     

Female philopatry and its social benefits among Bornean orangutans

Female philopatry in mammals is generally associated with ecological and sometimes social benefits, and often with dispersal by males. Previous studies on dispersal patterns of orangutans, largely non-gregarious Asian great apes, have yielded conflicting results. Based on 7?years of observational data and mitochondrial and nuclear DNA analyses on fecal samples of 41 adult Bornean orangutans (Pongo pygmaeus wurmbii) from the Tuanan population, we provide both genetic and behavioral evidence for male dispersal and female philopatry. Although maternally related adult female dyads showed similar home-range overlap as unrelated dyads, females spent much more time in association with known maternal relatives than with other females. While in association, offspring of maternally related females frequently engaged in social play, whereas mothers actively prevented this during encounters with unrelated mothers, suggesting that unrelated females may pose a threat to infants. Having trustworthy neighbors may therefore be a social benefit of philopatry that may be common among solitary mammals, thus reinforcing female philopatric tendencies in such species. The results also illustrate the diversity in dispersal patterns found within the great-ape lineage.     

Therapeutic applications of resveratrol nanoformulations

Resveratrol, or 3, 5, 4-trihydroxy-trans-stilbene, is a naturally occurring polyphenol present in several dietary sources such as grapes, soybeans, berries, pomegranate and peanuts. Resveratrol has received recent attention due to its diverse pharmacological activities. However, resveratrol clinical efficacy is limited due to its poor systemic bioavailability, of less than 1%, which is due to its low aqueous solubility, extensive first-pass metabolism and existence of enterohepatic recirculation. Therefore, in order to overcome these limitations, various nanocarriers including polymeric nanoparticles, solid lipid nanoparticles, liposomes, micelles and conjugates have been developed. These nanocarriers are able to enhance the bioavailability of resveratrol by modulating the P-glycoprotein, cytochrome P-450 enzymes and bypassing the hepatic first-pass effect. Here we review resveratrol nanoformulations for enhancing the efficacy of native resveratrol.     

Cyclodextrin-based delivery systems for dietary pharmaceuticals

Environmental Chemistry Letters - The food industry is increasingly seeking innovative solutions for enhancing the bioavailability and clinical efficacy of phytochemicals. In this regard,...     

Novel degradation pathway of 4-chloro-2-aminophenol via 4-chlorocatechol in Burkholderia sp. RKJ 800

Burkholderia sp. RKJ 800 utilized 4-chloro-2-aminophenol (4C2AP) as the sole carbon and energy source and degraded it with release of chloride and ammonium ions. The metabolic pathway of degradation of 4C2AP was studied and a novel intermediate, 4-chlorocatechol was identified as a major degradation product of 4C2AP using high-performance liquid chromatography and gas chromatography–mass spectrometry. Enzyme activities for 4C2AP-deaminase and 4-chlorocatechol-1,2-dioxygenase were detected in the crude extracts of the 4C2AP-induced cells of strain RKJ 800. The activity of the 4C2AP-deaminase confirmed the formation of 4-chlorocatechol from 4C2AP and the 4-chlorocatechol-1,2-dioxygenase activity suggested the cleavage of 4-chlorocatechol into 3-chloro-cis,cis-muconate. On the basis of the identified metabolites, we have proposed a novel degradation pathway of 4C2AP for Burkholderia sp. RKJ 800. Furthermore, the potential of Burkholderia sp. RKJ 800 to degrade 4C2AP in soil was also investigated using microcosm studies under laboratory conditions. The results of microcosm studies conclude that Burkholderia sp. RKJ 800 was able to degrade 4C2AP in soil and may be used to remediate 4C2AP-contaminated site. This is the first report of (1) the formation of 4-chlorocatechol and 3-chloro-cis,cis-muconate in the degradation pathway of 4C2AP and (2) bioremediation of 4C2AP by any bacterium.     

Comparative assessment of pesticide residues in grain, soil, and water from IPM and non-IPM trials of basmati rice

The integrated pest management (IPM) modules of pesticide schedule on Basmati rice were validated at field experiments conducted in Northern India for consecutive 3 years (2005–2008). The pesticide residues were found below the detectable limit (<0.01–0.001 mg/kg) in soil and irrigation water samples of Kaithal region. In Dehra Dun region of Uttrakhand, the residues of carbendazim in rice grains and soil were detected below <0.01 mg/kg level. In second year experiments (2006–2007), only four non-IPM soil samples indicated the presence of chlorpyrifos and endosulfan in the range of ND <0.001 to 0.07 mg/kg, out of 45 samples analyzed. Carbendazim applied as seed treatment at Dehradun and Kaithal field trials was found below detectable limit in both IPM and non-IPM rice grains (<0.01 mg/kg) and irrigation water (0.01 μl/ml). Chlorpyrifos was detected in five water samples from Kaithal and one from Pant Nagar in the range of 0.003–0.006 μl/L, α- and β-isomer of endosulfan in the range of 0.005–0.03, and 0.005–0.02 μl/ml, respectively, in one sample from Pant Nagar and two from Kaithal, out of a total of 22 samples. In the region of Uttrakhand and Uttar Pradesh during 2007–2008, four non-IPM samples of soil indicated trace levels of endosulfan, out of 16 samples analyzed. The residues were detected below detection limit for carbendazim (<0.01 mg/kg) in soil samples of Dehradun IPM fields and for endosulfan and carbendazim (0.001–0.01 μl/L) in water samples each from IPM and non-IPM fields of Uttar Pradesh. The results of 3-year trials of IPM module indicated basmati rice as safe and economical with pesticide residue-free rice grains.     

Strength,durability, and microstructure of self-compacting geopolymer concrete produced with copper slag aggregates

Environmental Science and Pollution Research - Lack of vibrations on fresh concrete negatively influences the compaction and thus the quality of concrete. This is particularly concerning with...     

An Experiment in Voluntary Environmental Regulation: Participation in EPA′s 33/50 Program

The U.S. EPA has initiated the 33/50 program to encourage firms to voluntarily reduce releases and transfers of 17 toxic chemicals. This paper evaluates the factors leading to participation in this program to assess its potential to augment more traditional command and control regulation. The results show that large firms with substantial toxic releases in unconcentrated industries are the most likely participants. The results also indicate that public information and awareness plays an important role and that EPA and other regulators can improve environmental performance by encouraging competition in environmental quality.